I’ve been on TRT for about six months primarily for ED. In my case, it took around three months before I noticed significant improvements in my symptoms. My energy levels increased, and there was a noticeable difference in sexual function. However, it’s important to monitor for side effects; I experienced some weight gain and mood swings initially. It’s crucial to possess a healthcare provider closely monitor your hormone levels and overall health during treatment. Each person’s response can vary, so adjusting the therapy to meet your specific needs is key.